Monoenergetic 290 MeV/n carbon-ion beam biological lethal dose distribution surrounding the Bragg peak
نویسندگان
چکیده
منابع مشابه
Monte Carlo computation of dose deposited by carbon ions in radiation therapy
Background: High-velocity carbon ion beams represent the most advanced tool for radiotherapy of deep-seated tumors. Currently, the superiority of carbon ion therapy is more prominent on lung cancer or hepatomas. Materials and Methods: The data for lateral straggling and projected range of monoenergetic 290 MeV/u (3.48 GeV) carbon ions in muscle tissue were obtained from the stopping and range o...
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Background: In radiation therapy with ion beams, lateral distributions of absorbed dose in the tissue are important. Heavy ion therapy, such as carbon-ion therapy, is a novel technique of high-precision external radiotherapy which has advantages over proton therapy in terms of dose locality and biological effectiveness.Methods: In this study, we used Monte Carlo method-based Geant4 toolkit to s...
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Introduction: Depth-dose distribution curve of protons in the matter has a maximum is called Bragg peak. Bragg peak of a monoenergetic proton beam is too narrow. The spread out Bragg peak should be created for full coverage of the tumor. The spread out Bragg peak is obtained in the depth of the tumor with superposition of the several Bragg peaks. The aim of this study was coverage of an eye tum...
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This work aimed at measuring cell-killing effectiveness of monoenergetic and Spread-Out Bragg Peak (SOBP) carbon-ion beams in normal and tumour cells with different radiation sensitivity. Clonogenic survival was assayed in normal and tumour human cell lines exhibiting different radiosensitivity to X- or gamma-rays following exposure to monoenergetic carbon-ion beams (incident LET 13-303 keV/mic...
متن کاملAlgorithms for Biological Dose Optimization in Ion Beam Radiotherapy
From 1997 until 2008 about 440 cancer patients were successfully treated in the ion therapy project at GSI. The patient treatment planning was performed with the software TRiP [1, 2]. A crucial part of the treatment planning is the particle number optimization with the goal to achieve a target dose distribution as close as possible to the prescribed biological dose distribution. The optimizatio...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-019-42600-4